Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line.
نویسندگان
چکیده
منابع مشابه
Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line
In contrast to mouse epidermal cells, human skin keratinocytes are rather resistant to transformation in vitro. Immortalization has been achieved by SV40 but has resulted in cell lines with altered differentiation. We have established a spontaneously transformed human epithelial cell line from adult skin, which maintains full epidermal differentiation capacity. This HaCaT cell line is obviously...
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ژورنال
عنوان ژورنال: The Journal of Cell Biology
سال: 1988
ISSN: 0021-9525,1540-8140
DOI: 10.1083/jcb.106.3.761